Amsterdam University Medical Centers, location AMC


The Amsterdam University Medical Centers, location AMC, includes the university hospital and the faculty of medicine of the University of Amsterdam. Over 7,000 people work at AMC to provide integrated patient care, fundamental and clinical scientific research, and teaching. Medical and biomedical research at the AMC enjoys international prestige. Within the AMC, the Amsterdam Reproduction & Development (AR&D) institute focuses on research with the ‘circle of life’ as framework: from conception through development back to conception. The focus is on the effects of diseases and interventions on reproductive organ function, conception, embryonic and foetal development, pregnancy and birth as well as child development and the effects on quality of life and long-term health.

Role in the Project

AMC is conducting research activities mainly in work package 6. Their focus will be on studying environmental determinants of anthropometric, glycaemic, cardiovascular and lipid-related health trajectories. For this, the researchers will make use of several cohorts, including the AMC-based Dutch Famine Birth Cohort, with data spanning from pregnancy to old age.

Dr Susanne de Rooij

Principal Investigator (PI)

Susanne is a psychologist and epidemiologist with specific expertise in early life stress, stress physiology and brain development. Her most recent research focuses on the effects of cognitive behavioural therapy in depressed pregnant women on neurodevelopment outcomes in children. In 2019, she received a grant to study the early life origins of dementia. She is also actively involved in science dissemination as coordinator of the stress knowledge centre ‘Stress Lab’ at the VU university in Amsterdam. Susanne’s role in LongITools is leader of work package tasks 6.2 and 6.3.


Professor Tessa Roseboom

Research Team

Tessa is Professor of Early Development and Health at AMC. Her current research focuses on the fundamental biological processes that underlie ‘developmental programming’ and on translation to current pregnancies, in developed and developing settings. These studies include observational and experimental studies of the long-term consequences of lifestyle interventions before and during pregnancy, obstetric interventions, hyperemesis gravidarum, and assisted reproduction techniques. In addition, she is actively involved in translating science into policy and practice, working directly with the Dutch Minister of Health in a programme aimed at giving each child the best possible start in life.


Irina Motoc

Research Team

Irina has a background in epidemiology and biochemistry, completing her education in Munich and Seattle. She is a postdoc researcher with the Dutch Famine Birth Cohort and will work on analysing environmental determinants of cardio-metabolic health trajectories in LongITools. Irina has previous experience harmonising data within the EU MINDMAP project. Her past and current research experiences have helped her understand (a little bit) how the environment gets under the skin, a life-long endeavor which she is committed to.