Imperial College London


Imperial College London (ICL) is one of the leading science universities in the world. Imperial’s School of Public Health (ISPH) is an organisational leader in public health research. ISPH hosts two medical research centres including the MRC PHE Centre for Environment and Health (MRC Centre). ISPH also includes the Department of Epidemiology and Biostatistics (EBS) which has established an international leading reputation in the development of statistical approaches to analyse multiple sets of omics data in large epidemiological studies. The project will leverage ICL’s expertise in biostatistics and life-course modelling approaches.

Role in LongITools

ICL will be leading WP3 and will be responsible for the development of statistical methods and strategies to explore exposome data over the life-course.

Dr Marc Chadeau-Hyam

Principal Investigator (PI) and WP3 Leader

Marc is a Reader in Computational Epidemiology and Exposome Sciences at ICL. His expertise is in the analysis and integration of omics data. His current research is focused on the joined use of omics profiling techniques and network topologies to explore the regulatory cascades triggered by the exposome. Marc has steered several methodological projects on the development and application of novel statistical techniques to explore the complex molecular sequelae of the exposome, including socioeconomic factors. He leads work package 3 in LongITools, which is responsible for the development of exposome profiling and integration tools, and is also involved as WP leader in the EXPANSE project, one of the eight other projects in the European Human Exposome Network.


Professor Marjo-Riitta Järvelin


Marjo-Riitta is Professor and Chair in Life-course Epidemiology at ICL and Scientific Director of the Northern Finland Birth Cohort Study (NFBC). She holds a visiting professorship at Brunel University London and a part-time professorship at the University of Oulu. She is honorary consultant for Imperial College Healthcare NHS Trust, UK. Marjo-Riitta has been running large-scale population-based and clinical studies for over 30 years, working on the genetic, epigenetic and early life environmental origins of multi-factorial diseases and disorders. She is involved in multiple projects on analytical strategies/methods developments for multi-phenotypes and longitudinal studies. In particular she is/has been the coordinator of many large scale projects including EURO-BLCS, DynaHEALTH and PREcisE. She will contribute to LongITools through her long-lasting expertise in life-course epidemiology and will be a key player in WP3 research activities.

Dr Abbas Dehghan


Abbas is a Reader in Cardiometabolic Disease Epidemiology at ICL. He is a member of the CHARGE steering committee, a consortium of epidemiologic studies to facilitate collaborative projects on various omics platforms, where he has successfully led a number of large international projects. His research focuses on molecular determinants of cardiometabolic health. He has experience in working with various omics data in epidemiologic settings including genomics, epigenomics and metabolomics. Abbas has been a Co-Investigator of COMBI-BIO project, an FP7 funded project on metabolomics signatures of atherosclerosis, and part of international collaborative projects that were funded by the National Institutes of Health (NIH) and the EU. Abbas will bring his expertise in cardiometabolic health and their molecular determinants to the LongITools project.