LATEST: SPOTLIGHT: Exposure to fine particulate matter (PM2.5) in adults is associated with immune cell gene expression related to inflammation, the electron transport chain and cell cycle regulation (April 25)
23/05/2025 - Amanda Rundblad et al. Environmental Epigenetics. LongITools authors: Amanda Rundblad, Siddhartha Das, Gina Ginos, Jason Matthews, Kirsten Holven, Stine Marie Ulven - University of Oslo, Erasmus MC
Exposure to air pollution and an unhealthy built environment increase disease risk by impacting metabolic risk factors and inflammation, potentially via epigenetic modifications and effects on gene expression. In this study, we aimed to explore associations between fine particulate matter (PM2.5), black carbon, ozone, nitrogen dioxide, distance to nearest water body, normalized difference vegetation index, and impervious surface and gene expression profiles in adults.In conclusion, PM2.5 is strongly associated with various gene expression profiles, which provide information about the underlying mechanisms of the detrimental health effects of exposure to PM2.5.